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The cough

Lecture course: “Cough. New aspects in sputum evacuation biomechanics.”
For the first time ever prof Gennadiy M. Chernyakov provides a way for understanding biophysical being of cough phenomenon using systemic approach in analysis. Each of the 12 parts abstracts have been translated into English.  The author is ready to reply any questions by e-mail:
genmich1@mail.ru.
 

Part 1.
General information about cough. Diversiform cough or diversiform reasons of cough generation. What kind of cough variations are useful to identify. When it is necessary to keep going cough or, on the other hand, decelerate it. Is it true, that cough is “defensive reflex”? What is the physical functionality of cough. Further lecture contents information.

Part 2.
Effects potentially exist in liquid substance while contacting with high speed airflow: number of mechanisms and number of conditions for this ability.

 

Part 3.
Analysis of the physical factors that are dictated by serial cough impulses in structure of its pattern. Cough impulses seriation as a general phenomenon that tells the difference between cough and other forced expiration maneuvers. The speed of clear fissure of glottis opening: its importance for further events making each cough impulse.  

 

Part 4.
What happens in pressurized air mass in lungs while explosive fissure of glottis opening. Physical conditions associated with sudden drop of extreme pressure in the intrapulmonary airways volume. The interface between air intrapulmonary space and condensed substance in lungs under entrapped air compression: investigation of force factors in the line of interface.

 

Part 5.
Physical mechanism of the phenomenon of extreme air pressure relief in the lower airways volume. The manner in which extreme air pressure relief in airways effects on condition of mucus spread on bronchus internal surface. For what reason the phenomenon of extreme air pressure relief in the lower airways volume is of equal strength to bronchus wall stroke from lung parenchyma. The way how both the depth of previous inspiration and the value of entrapped air compression produce an effect on the phenomenon of extreme air pressure relief. Implication of the air flow in itself (in other words, directional gas mass motion) for the purpose of cough pattern.

 

Part 6.
Force factors that get mucus into a state of moving: more precise definition of its genesis. Analysis of mistakes origin in calculation of maximum air flow speed (at a level of trachea) for initial moments after fissure of glottis opening in the process of cough. Concepts of the 2 periods of involving mucus to removable condition: one of which is mucus displacement to the central part of airways through mucosal plications. Arguments for investigation of the phenomenon of extreme air pressure relief in the lower airways volume as a self consistent event (process) in physical cough arrangement and parametric characteristics of this phenomenon. Analysis of physical characteristics attributable to air flow in closed loop line having variable cross-section area.

 

Part 7.
Different mechanisms of mucus displacement in the direction of trachea in small and large bronchi due to single (continuous) air flow in the area of its low and high linear speed. Concepts of necessity for longitudinal mucus displacement mechanisms conjugating in small and large bronchi segments.

 

Part 8.
Analysis of bronchial wall organization providing ability of air compression in isolated lung volume and realization of the phenomenon of extreme air pressure relief in the lower airways volume. Implication of intrapulmonary air tubes smooth muscle apparatus in native forceful arrangement of cough patterns.

 

Part 9.
Analysis of facts conjugated with contractility loss of intrapulmonary air tubes smooth muscle apparatus. Explanation of the true mechanisms of phenomenon that is incorrectly interpreted as “the relief of bronchospasm” in consequence of bronchial spasmolytics administration. The manner  in which not naturally-occurring relaxation of intrapulmonary air tubes smooth muscle apparatus damages sputum evacuation (expectoration) from lower airways. Genesis of dysfunctional (troubled) sputum transfer zone in the area where disconnecting of 2 sputum transfer mechanisms exists (mechanisms that work in small and large bronchi in the presence of drug-induced relaxation of intrapulmonary air tubes smooth muscle apparatus). The phenomenon of excessive sputum accumulation near the distal line of dysfunctional (troubled) sputum transfer zone.

 

Part 10.
The phenomenon of sputum reallocation from its excessive accumulation area near the distal line of dysfunctional (troubled) transfer zone. Analysis of critical conditions in the lower airways space connected with the genesis of crucially new effects due to external aggression to airways functional organization and therefore not having natural compensatory mechanisms.

 

Part 11.
Physical mechanisms of airways wall edema genesis due to cough existing on the background of relaxation of bronchi smooth muscle apparatus (edema that is incorrectly interpreted as unclear etiology inflammation appearance).

 

Part 12.
Summary.

Scientific Center of Children Health

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